INTERACTIONS between Cocktail Ingredients
Warfarin and aspirin and anti-inflammatories including Celebrex will have interactions with cocktail ingredients. Whether or not the Curcumin, Enzyme Co-Q10, and Flax seed oil interact significantly will also have to be watched.
Or the warfarin can be changed to low molecular weight heparin while you are on these ingredients, or other ingredients can be substituted. But patients who are anticoagulated will need to have their blood checked and anticoagulant status and dosage reviewed by their doctor.
Multi-Drug Interaction Checker at www.medscape.com
From: drug digest, www.drugdigest.org
I entered the ingredients for the cocktail except shark oil/squalamine and Vitamin B. These are the six interactions listed.
Interactions between the following drugs and herbs:
Acetyl Cysteine Oral Solution
Acetyl salicylic acid
Co Q 10
Vitamin B-12 Tablets
(Note: Herbal products are not subject to review or approval from the FDA. Not all of the risks, side effects, or interactions associated with the use of herbal products have been studied. Not all drug interactions are known or reported in the literature, and new drug interactions are continually being reported. This information is provided only for your education and for you to discuss with your personal healthcare provider. )
COENZYME Q-10 (in Co Q 10) may interact with TURMERIC (in Curcuma species) Both coenzyme Q-10 and turmeric contain chemicals that may reduce the blood’s ability to form clots. When taken together, they can increase the risk of dangerous bleeding. You may need frequent blood tests to make sure that your blood is clotting properly. In addition, both coenzyme Q-10 and turmeric contain substances that may lower blood sugar levels. If they are used together, blood sugar levels may become too low and symptoms such as shakiness, sweating, confusion, and distorted speech, may result. In general, coenzyme Q-10 and turmeric should not be taken at the same time. If they are used together and bleeding is uncontrolled or blood sugar levels become too low, either coenzyme Q-10 or turmeric or both may need to be stopped. You may want to ask your healthcare provider about this potential interaction if you think you are having problems. This interaction is poorly documented and is considered minor in severity.
ALCOHOL may interact with ASPIRIN (in Acetylsalicylic acid)
Both aspirin and alcohol (ethanol) can cause stomach irritation and may potentially damage the lining of the stomach. In some cases, this damage may be so severe that it causes a bleeding ulcer. When aspirin and alcohol are used at the same time, the risk of developing a bleeding ulcer may be increased for up to 36 hours after the dose of aspirin is taken. To minimize this risk, avoid using aspirin for 12 hours after alcohol has been consumed. If it is not possible to allow this much time to pass, consider using either enteric-coated aspirin, extended-release aspirin, or a buffered, effervescent aspirin product. You may want to ask your healthcare provider about this potential interaction if you think you are having problems. This interaction is poorly documented and is considered minor in severity.
TURMERIC (in Curcuma species) may interact with ASPIRIN (in Acetylsalicylic acid)
Turmeric contains chemicals that can affect the stickiness of blood components called platelets. Platelets are partly responsible for forming blood clots that stop bleeding from injuries. When taken together with drugs like aspirin that decrease the blood’s ability to clot, large amounts of turmeric supplements can increase the risk of dangerous bleeding or may cause aspirin not to work well enough. Inform your doctor before taking aspirin with turmeric or any other herbal supplement. If you do take turmeric at the same time as aspirin, your doctor may want to give you more frequent blood tests to make sure that your blood is clotting properly. Small amounts of turmeric used as seasoning in foods do not usually affect blood clotting. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems. This interaction is poorly documented and is considered moderate in severity.
COENZYME Q-10 (in Co Q 10) may interact with ASPIRIN (in Acetylsalicylic acid) Because it is similar in shape to vitamin K, which helps blood to clot, coenzyme Q-10 may increase the blood’s tendency to form clots. When coenzyme Q-10 is taken together with drugs like aspirin that decrease blood clotting, the drug may not work as well and blood clots may occur. Coenzyme Q-10 should not be taken while aspirin is being used to control blood clots. Individuals who take both may need more frequent blood tests to make sure that blood is clotting properly. Those, who experience problems, may have to stop taking coenzyme Q-10 until aspirin is discontinued. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems. This interaction is poorly documented and is considered moderate in severity.
Addition Interaction between HIGH levels of Zinc, Iron and Calcium…
It may be that high levels of these minerals in the blood will promote the growth of breast lumps. The Zinc blood level is high in this cocktail’s users, it would be a provident thing to keep an eye on calcium and iron as well.
“Our data raise the possibility that relatively high levels of zinc, iron and calcium in benign breast tissue may be associated with a modest increase in risk of subsequent breast cancer”.
Full Free Text is available at http://cebp.aacrjournals.org/cgi/content/full/16/8/1682
You should always consult with your physician before taking any new over-the-counter supplements or drugs.